2026 Scientific Program 

Download the CGC 2026 Scientific Agenda 

All session times are in US Central Daylight Time.
Sessions will be recorded and available for later viewing for our participants in different time zones.
Sessions are subject to change.

In-Person Unconference

Unconference participation incurs an additional registration fee.
Click here for more information about the Unconference.

1:00 PM - 6:00 PM

Unconference Session #1

In-Person Unconference

Unconference participation incurs an additional registration fee.
Click here for more information about the Unconference.

8:00 AM - 12:00 PM

Unconference Session #2

Opening of the 17th Annual Meeting of the Cancer Genomics Consortium

1:00 - 1:05 PM

Welcome
Cate Paschal, Seattle Children’s Hospital, WA

1:05 - 1:15 PM

Presidential Address
Fady Mikhail, University of Alabama at Birmingham, AL

1:15 - 2:15 PM

Keynote Presentation
Gigi Lozano, University of Texas MD Anderson Cancer Center, TX

2:15 - 3:15 PM

Invited Session 1: TED-Style Session: Expanding Access and Representation in Genomic Research
Moderator: Cinthya Zepeda Mendoza, Mayo Clinic, MN

Speakers:
Debra Murray, Baylor College of Medicine, TX
Deborah Ritter, Baylor College of Medicine, TX

3:15 - 3:45 PM

Coffee Break in the Exhibit Hall
Science Café Presentations

3:45 - 4:00 PM

Platinum Exhibitor Showcase
(No CME or CEUs available)

4:00 - 4:15 PM

Platinum Exhibitor Showcase
(No CME or CEUs available)

4:15 - 4:45 PM

CGC Updates and Business Meeting
Fady Mikhail, University of Alabama at Birmingham, AL

4:45 - 5:00 PM

Award Presentations

Platform Session 1: Tech and Trainee Awardee Abstracts

Diagnostic testing for multiple myeloma in the era of precision medicine
Prasad Kopparapu, Indiana University School of Medicine, IN

Pairing molecular technologies with conventional cytogenetics to clarify atypical translocation t(8;21) patterns in AML
April Suarez, Fred Hutch Cancer Center, WA

Single-cell, single-nuclei, and spatial transcriptomics reveals signature-specific microenvironments in hepatoblastoma
Abhishek Murti, University of California, San Francisco, CA

High-resolution multi-omic LINE-1 retrotransposon activity and structural variation in non-small cell lung cancer
Yingshan Wang, Texas A&M Institute of Biosciences and Technology, TX

6:00 - 8:00 PM

Welcome Reception
CGC Exhibit Hall, Legends Ballroom

Case Studies

Cytogenetic analysis reveals underlying therapy-related myeloid neoplasm
Celeste Eno, Cedars-Sinai Medical Center, CA

Comprehensive molecular characterization of isolated tetrasomy 13 in acute myeloid leukemia: A case report
Dibyendu Dutta, State University of New York Upstate Medical University, NY

Comprehensive characterization of a complex multiple myeloma genome
Nesrin Hasan, University Hospitals, OH

Only the hits: Assessment for 'double hit' lymphoma using Hi-C sequencing
Phillip Michaels, Brigham and Women's Hospital, MA

Invited Session 2: Harmonizing Cancer Variant Interpretation: New and Updated Standards for Clinical Practice
Moderator: Gordana Raca, Cincinnati Children's Hospital Medical Center, OH

Marilyn Li, Children's Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, PA
Fady Mikhail, University of Alabama at Birmingham, AL
Karen Tsuchiya, Nationwide Children’s Hospital, OH

10:00 - 10:45 AM

Coffee Break in the Exhibit Hall
Science Café Presentations

10:45 AM - 12:00 PM

Platform Session 2: Solid Tumors and Cancer Predisposition

Advances in cancer genomics landscape: Final report from the CGC Central Nervous System (CNS) Tumors Taskforce
Madina Sukhanova, Northwestern University Feinberg School of Medicine, IL

Chromothripsis and distinct copy number alteration patterns across histology and staging in wilms tumor
Ashan Dayananda, Nationwide Children's Hospital, OH

AVIL as a therapeutic target in GBM: Insights into cell death mechanisms
Adelaide Fierti Amanor Sackey, University of Virginia, VA

Cancer predisposition variants in mRNA processing genes in a pediatric pineoblastoma cohort
Ying-Chen Hou, Nationwide Children’s Hospital, OH

Evidence-based gene curation from the ClinGen Childhood, Adolescent and Young Adult Cancer Predisposition GCEP
Pamela Ajuyah, Broad Institute of Massachusetts Institute of Technology and Harvard University, MA

12:00 - 1:15 PM

Exhibit Lunch and Networking
Exhibit Hall and Foyer

1:15 - 1:45 PM

Diamond Exhibitor Showcase
(No CME or CEUs available)

1:45 - 2:00 PM

CCGA Updates
Jennelle Hodge, Indiana University, IN
Katie Schieffer, Nationwide Children’s Hospital, OH

2:00 - 2:15 PM

VICC Updates
Alex Wagner, Nationwide Children’s Hospital and The Ohio State University, OH

2:15 - 3:15 PM

Keynote Presentation
Philip Lupo, Emory University, GA

3:15 - 4:00 PM

Coffee Break in the Exhibit Hall
Science Café Presentations

Invited Session 3: Adapting Variant Interpretation Frameworks in Community Settings
Moderator: Madina Sukhanova, Northwestern Feinberg School of Medicine, IL

Wesley Goar, Nationwide Children's Hospital, OH
Jason Saliba, Washington University School of Medicine, MO
Alex Wagner, Nationwide Children’s Hospital and The Ohio State University, OH

Poster Session (Odd Numbered Posters)
Cash Bar
CGC Exhibit Hall

6:30 – 8:00 PM

Early Career Social
For attendees in training or recently out of training
*Pre-registration is required. Please sign-up during meeting registration.

Case Studies

Determining the constitutional origin of a ring chromosome 21 in an acute myeloid leukemia patient and her sibling donor
Rebecca Smith, Vanderbilt University Medical Center, TN

Unique case of a mosaic 5q deletion in an individual with multiple colon polyps
Ankita Jhuraney, University of Washington, WA

Dynamic mosaic copy number gains identified by concurrent exome sequencing and microarray testing in a neonate
Avinash Dharmadhikari, Children's Hospital Los Angeles, CA

Sibling donor-derived hematopoietic cells confounding chromosomal microarray interpretation in a meningioma case
Jinbo Fan, University of Virginia, VA

9:00 - 10:00 AM

Keynote Presentation
Annette Kim, University of Michigan, MI

10:00 - 10:45 AM

Coffee Break in the Exhibit Hall
Science Café Presentations

10:45 AM - 12:15 PM

Platform Session 3: Emerging Technologies

Improving the detection of genomic rearrangements in lymphoma: An evaluation of Hi-C FFPE sequencing compared to FISH
Adam Smith, Labcorp, NC

Six-base sequencing of aqueous humor cell-free DNA from retinoblastoma patients
Zejuan Li, Houston Methodist Hospital, TX

RNAseq vs. whole transcriptome sequencing: selecting the right workflow for fusion detection for clinical applications
Rashmi Kanagal-Shamanna, University of Texas MD Anderson Cancer Center, TX

Rapid multi-omics profiling of acute leukemia using nanopore long-read sequencing
Derek Wong, Children’s Hospital of Philadelphia, PA

Multi-omic MMRD testing of tumours and cfDNA using an integrative DNA sequencing and methylation panel
Trevor Pugh, Princess Margaret Cancer Centre, ON, Canada

Ultrarapid methylation classification and rapid comprehensive genomic profiling of pediatric CNS tumors
Feng Xu, Children's Hospital of Philadelphia, PA

12:15 - 1:30 PM

In-Person Round Table Discussions with Lunch
Please sign up for table topics during meeting registration. Click here for more information about the In-Person Round Table Discussions.

1:30 - 1:45 PM

Platinum Exhibitor Showcase
(No CME or CEUs available)

1:45 - 2:00 PM

Platinum Exhibitor Showcase
(No CME or CEUs available)

2:00 - 2:15 PM

New CGC Programs Update
Melanie Babcock, Variantyx, PA

2:15 - 2:30 PM

CGC Working Group Updates
Fady Mikhail, University of Alabama at Birmingham, AL

2:30 - 3:45 PM

Platform Session 4: Bioinformatics and Variant Curation

Identification of tumor-associated antigens with multi-cancer therapeutic potential
Daniel Wickland, Mayo Clinic, FL

Automating subtype-specific cancer gene prioritization at the OncoTree scale using Large Language Models (LLMs)
Suhasini Lulla, Baylor College of Medicine, TX

Centralized genomic annotation to enable multi-site biomarker-driven oncology trials
Thuy Vu, University of Texas MD Anderson Cancer Center, TX

Predictive accuracy of liquid biopsy for comprehensive genomic profiling of solid tumors
Nathan Hassel, Kaiser Permanente, CA

AmpliconSuite and AmpliconRepository: Enabling ecDNA biology at scale
Jens Luebeck, University of California San Diego, CA

3:45 - 4:30 PM

Coffee Break in the Exhibit Hall
Science Café Presentations

Invited Session 4: Establishing Clinical Pharmacogenomics Testing: Assays, Implementation, and Resources

Wahab Khan, Dartmouth College, NH
Stuart Scott, Stanford University, CA
Sherin Shaaban, University of Utah School of Medicine, UT

Bowling at Lucky Strike
The Escape Game (arrive 15 minutes early)
Line Dancing

Platform Session 5: Hematologic Malignancies

Gene amplification in AML and MDS - insights from the first-year NCI-MyeloMATCH trial
Thaiha Nguyen, Fred Hutchinson Cancer Research Center, WA

Optical genome mapping improves detection of cryptic structural variants in chronic myelomonocytic leukemia
Kim Hoang Ly Nguyen, University of Texas MD Anderson Cancer Center, TX

Cryptic rearrangements and enhancer hijacking are commonly detected in lymphoid malignancies by optical genome mapping
Xiaoming Wang, University of Michigan, MI

Integrated cytogenomic profiling identifies distinct genomic clustering and predictors of TTFT in Indian CLL
Hemani Jain, Tata Memorial Centre, Panvel, India

Hematology outcomes of general population with MDS-related chromosomal alterations or mutations
Huan Mo, National Human Genome Research Institute, National Institutes of Health, MD

Characterization of DDX41 germline predisposition syndrome: A single site analysis
Catherine Levy, Huntsman Cancer Institute, UT

10:30 - 11:00 AM

Coffee Break in the Exhibit Hall

Invited Session 5: Navigating Variant Classification in Low Penetrance Genes and Variants
Moderators: Jasmine Baker, Baylor College of Medicine, TX

Sharon Plon, Baylor College of Medicine, TX
Marcy Richardson, University of California, San Diego, CA
Ryan Schmidt, University of Southern California, Children’s Hospital Los Angeles, CA

12:00 PM

Closing Remarks
Fady Mikhail, University of Alabama at Birmingham, AL
Cate Paschal, Seattle Children’s Hospital, WA

Download the CGC 2026 Scientific Agenda