2020 Scientific Program


Recordings for Tuesday, August 5 are now available on the CGC 2020 Virtual Meeting Platform for registered attendees.
Session recordings will be available for registered attendees through December 2020.


Tuesday, August 4, 2020


The CGC 2020 Virtual Annual Meeting will be presented in the eastern daylight times (EDT) shown below.

After each presentation, recordings will be available on the virtual meeting platform for those registrants in different time zones, and will be posted later on the CGC website for on demand access for CGC members.

Looking to Join the Virtual Meeting? Once you have  registered, please check your email for instructions and your link to join the Virtual Meeting Platform. Search for an email from "CGC 2020 Virtual Annual Meeting <no-reply AT pathable.com>" with subject "2020 CGC Virtual Annual Meeting - Access the Virtual Platform Now".


Opening of the 11th Annual Cancer Genomics Consortium


10:00 - 10:05 AM

Yassmine Akkari, Legacy Health

10:05 - 10:15 AM

Presidential Address
Adrian Dubuc, Harvard Medical School

10:15 - 11:00 AM

Introduction: Fady Mikhail, University of Alabama at Birmingham

Keynote Presentation

The many genomic roads to acute lymphoblastic leukemia
Charles Mullighan, St. Jude Children's Research Hospital

Speaker Q & A

11:00 - 11:30 AM     

Diamond Vendor Showcase: Illumina
(No CME or CEUs available)

DNA methylation profiling to predict risk recurrence in meningioma
Gelareh Zadeh, University Health Network, University of Toronto 

Development and validation of an individualized predictor of 5-year recurrence risk in meningioma
Farshad Nassiri, University of Toronto


Hematologic Malignancies

Moderator: Niroshi Senaratne, University of California Los Angeles

11:30 AM - 12:00 PM

FISHues on tissues: Paraffin pitfalls, puzzles and predicaments
Rhett Ketterling, Mayo Clinic

Speaker Q & A

12:00 - 12:45 PM 

Abstract Presentations                  


PAX5 partial tandem duplication in pediatric B-ALL: Incidence and clinical, morphologic and genetic correlations
Gordana Raca, Children's Hospital Los Angeles


NUP98 rearrangements in hematologic malignancies: A 4-year review from the genomics laboratory
Xinjie Xu, Mayo Clinic


RNA-based fusion studies critically improves clinical management of acute leukemias 
Leonardo Boiocchi, Massachusetts General Hospital

Session Q & A

12:45 - 1:00 PM

Platinum Vendor Showcase: Bionano
(No CME or CEUs available)

Next generation cytogenetics: Genome imaging for comprehensive germline and somatic structural variant detection
Alexander Hoischen, Raboud University Medical Center, Nijmegen, The Netherlands


1:00 - 3:00 PM


Break: Poster Session and Exhibit Hall Open


Approaches to CNS Tumors

Moderator: Alan LennonPathGroup

3:00 - 3:30 PM          

Integrating molecular data into the diagnosis of CNS tumors: Strategies and perspectives
David Meredith, Brigham and Women's Hospital Harvard Medical School

Speaker Q & A

3:30 - 4:00 PM
Abstract Presentations


Near-haploidization molecularly defines giant cell glioblastoma
Daynna Wolff, Medical University of South Carolina


Characterization of BCOR ITD in pediatric solid tumors using targeted NGS panel and whole transcriptome sequencing
Jinhua Wu, Children's Hospital of Philadelphia

Session Q & A

4:00 - 4:30 PM   

Diamond Vendor Showcase: Agilent
(No CME or CEUs available)

Neoplastic chromosomal microarray analysis: the Legacy Health experience
Yassmine Akkari, Legacy Health   

Novel Approaches for Genome Analysis

Moderator: Linda Baughn, Mayo Clinic

4:30 - 5:15 PM
Abstract Presentations

Genomic gymnastics: using RNAseq and mate pair sequencing to collaboratively decipher structural variation
Beth Pitel
Mayo Clinic
First Place Technologist Award


Utility of whole genome optical mapping (WGOM) in cytogenetic analysis of solid tumors and hematologic malignancies (HM)
Nikhil Sahajpal, Augusta
Second Place Technologist Award


One test to rule them all? The utility of nanopore sequencing for variant detection in hematological malignancies
William Glen, Medical University of South Carolina

Session Q & A

5:15 - 5:30 PM

Platinum Vendor Showcase: PathGroup
(No CME or CEUs available)

Endeavor Comprehensive Genomic Profiling
Pranil Chandra, PathGroup

5:30 - 6:15 PM 


Introduction: Stuart Schwartz, LabCorp

Keynote Presentation

Using long-read technologies to explore the structure and function of the human genome
Evan Eichler, University of Washington

Speaker Q & A

6:15 - 6:45 PM               

CGC After Hours

Do No Harm : Genetic Testing for Hereditary Cancer 2020
Jone Sampson, Oregon Health & Sciences University

Speaker Q & A

6:45 - 8:30 PM           

Select Abstract Presentations:

Tumor testing of DNA repair genes in high grade serous ovarian cancer (HGSOC); a potential tool for personalized therapy
Elizabeth McCready, McMaster University

KAT6A amplification is associated with shorter PFS and OS in serous endometrial carcinoma
Gokce Toruner, MD Anderson Cancer Center

Validation of CNA detection using an amplicon-based targeted NGS panel for hematological malignancies
Fei Yang, Oregon Health & Science University

ChromoSeq: WGS-based karyotyping for hematologic malignancies
Eric Duncavage, Washington University School of Medicine

Integrated informatics analysis of cancer-related variants with OpenCRAVAT
Kymberleigh Pagel, Johns Hopkins University

The Good, the Bad, and the Ugly of SNP Array Testing for Cutaneous Melanocytic Neoplasms
Katherine Geiersbach, Mayo Clinic

Accurate neoantigen prediction depends on mutation position relative to patient-specific MHC anchor locations
Huiming Xia, Washington University School of Medicine



Wednesday, August 5, 2020


Looking to Join the Virtual Meeting? Once you have registered, please check your email for instructions and your link to join the Virtual Meeting Platform. Search for an email from "CGC 2020 Virtual Annual Meeting <no-reply AT pathable.com>" with subject "2020 CGC Virtual Annual Meeting - Access the Virtual Platform Now".     

10:00 - 10:15 AM

Platinum Vendor Showcase: Pillar BioSciences
(No CME or CEUs available)

Productivity-focused solutions for precision oncology
Gang Song, 
Pillar BioSciences

10:15 - 11:00 AM

Panel Discussion: Challenges in Oncology Chromosomal Microarray Testing

Stuart Schwartz, LabCorp
Daynna Wolff,
Medical University of South Carolina
Mary Shago, 
The Hospital for Sick Children 

Fady Mikhail, 
University of Alabama at Birmingham
Linda Baughn,
Mayo Clinic

11:00 - 11:30 AM    

Diamond Vendor Showcase: Archer
(No CME or CEUs available)

Design, Validation and Implementation of Expanded NGS panels for Precision Oncology in an Integrated Healthcare System
Laila Mnayer, Hartford Hospital


11:30 AM - 12:15 PM

Introduction: Yassmine Akkari, Legacy Health

Keynote Presentation

Cancer Genomics Drives Pediatric Cancer Precision Medicine
Elaine Mardis, 
Nationwide Children's Hospital

Speaker Q & A


Predication and Characterization of Metastasis

Moderator: Cate Paschal, Seattle Children's Hospital

12:15 - 1:00 PM
Abstract Presentations


Genomic characterization of brain metastases identifies drivers of metastatic lung adenocarcinoma 
David Shih, University of Texas MD Anderson Cancer
First Place Trainee Award


Spatiotemporal patterns of metastatic spread and survival from MSK-IMPACT, a large-scale prospective clinical sequencing
Bastien Nguyen, Memorial Sloan Kettering Cancer Center


Molecular heterogeneity in glioblastoma multiforme influences variant clonality and neoantigen prediction accuracy
Megan Richters, Washington University School of Medicine

Session Q & A

1:00 - 3:00 PM

Break: Poster Session and Exhibit Hall Open


3:00 - 3:15 PM

Platinum Vendor Showcase: Cepheid
(No CME or CEUs available)

Easier and Faster BCR-ABL Monitoring with Cepheid's Xpert® BCR-ABL Ultra
Scott Campbell, Cepheid

Evaluation and Implementation of Xpert® BCR-ABL Ultra in a Large Health System
Yi Ding, Geisinger Medical Center


Moderator: Obi Griffith, Washington University of St. Louis

3:15 - 4:15 PM
Abstract Presentations

Identification of predicted neoantigen vaccine candidates in follicular lymphoma patients
Cody Ramirez, Washington University School of
Second Place Trainee Award


Clinical considerations for migration between genome assemblies: Lessons learned in moving to GRCh38
Sabah Kadri, Ann and Robert H. Lurie Children's Hospital


Unique cancer cytogenetics knowledgebase integrated with a machine learning system to improve clinical reporting
Soheil Shams, BioDiscovery, Inc


Integrating cytogenomic and sequence variants in the GA4GH variation representation specification
Alex Wagner, Washington University School of Medicine

Session Q & A
4:15 - 4:45 PM

Simultaneous Chat Rooms for Round Table Discussions

Topics selected by participants during meeting registration

4:45 - 5:00 PM

Platinum Vendor Showcase: Oxford Gene Technology
(No CME or CEUs available)

Genomic evaluation of chronic lymphocytic leukemia: first steps in transitioning from an aCGH+SNP platform to a targeted NGS CNV detection approach 
Fléchère Fortin, CIUSSS de lEstrie CHUS

5:00 - 5:45 PM

Introduction: Kilannin Krysiak, Washington University of St. Louis

Keynote Presentation

Mechanisms driving the rapid evolution of cancer genomes
David Pellman, Brigham and Womens Hospital Harvard Medical School

Speaker Q & A

5:45 - 8:00 PM

CGC After Hours

CGC Initiative: A Resource for our Clinical Genomics Community: the Compendium of Cancer Genome Aberrations (CCGA)
Jennelle Hodge, Indiana University

Trainees and Mentors Session

Community engagement for crowd-sourcing clinically relevant somatic variants, the CIViC experience
Kilannin Krysiak, Washington University School of Medicine

Use of a targeted gene panel to inform treatment decisions for patients with AML
Erica Barnell, Washington University School of Medicine

De novo constitutional PATRR-mediated t(3;8) balanced translocation associated with clear cell renal cell carcinoma
Marilena Melas, Nationwide Children's Hospital

Curation of genetic variants in childhood cancers within the Clinical Genome Resource (ClinGen)
Wan-Hsin Lin, ClinGen

Germline EGFR Variants Over-Represented in Adolescent and Young Adult (AYA) Females with Adrenocortical Carcinoma
Sara Akhavanfard, Cleveland Clinic / Nationwide Children's Hospital

CGC Happy Hour With Special Musical Guest

*Speakers and timing subject to change